The Science and Experience of Energy is a community building initiative led by Martin Picard, PhD, a mitochondrial psychobiologist and professor in the depar…
3:252K views · 2mo ago · 3:25
Our body is a dynamic collective. This is true at the level of our cells. And also at smaller scales, at the level of our mitochondria. In this video, I explore how the mitochondrial collective of a cell receives signals, integrates information, and helps shape cell fates. Mitochondria match cell behavior with the greater good of the whole body.
3:261.3K views · 2mo ago · 3:26
Why do some people recover quickly from illness or injury, while others don’t? Throughout my life I have been fascinated by the healing process, and what we can do to achieve optimal health. In this video, I share a reflection about the human experience of healing that continues to inspire me in my research on mitochondria, energy, and human health.
3:501.5K views · 3mo ago · 3:50
Energy is the fundamental force that enables life, health, and healing. Approaches like genome sequencing provide static snapshots of the instructions encoded into our DNA. However, each person is unique, and genes don't fully determine when and how people develop common chronic illnesses. How we age and our ability to heal also are dynamic features that aren’t encoded in our genes.
3:162.5K views · 3mo ago · 3:16
Mitochondria do much more than just transform energy to power our cells. They serve as a portal between the small-scale physical-chemical processes that give rise to life, and larger-scale phenomena, like consciousness, that make us human. This video provides insight on the dynamic, social nature of mitochondria and the roles they play in transforming biochemical energy from food into signals, and into the human experience.
3:082.4K views · 5mo ago · 3:08
Energy is the driving force of life that powers all of our complex biological functions, and all of these functions require resistance. Resistance is what transforms energy so it can do meaningful work in our bodies. This short explainer video provides an introduction to the Energy Resistance Principle (ERP).
1:07:022.5K views · 5mo ago · 1:07:02
In this video, Martin Picard shares his tenure talk at Columbia University, including the origins of his research program. He describes progress that his lab has made across five research themes: mitochondrial disease, aging, cell-free mitochondrial DNA (cf-mtDNA), the brain, and technological innovation. Martin also describes future plans of the Mitochondrial Psychobiology Lab.
8:24759 views · 9mo ago · 8:24
2025 MiSBIE Symposium at Columbia University December 12, 2025 A fabulous and stimulating day distilled into eight minutes.
26:24292 views · 9mo ago · 26:24
Part I – MiSBIE Study rationale and protocol ⎸ Welcome MiSBIE team, collaborators, partners – Martin Picard Agenda for today’s MiSBIE progress meeting – Caroline Trumpff MiSBIE Study overview – Martin Picard Rationale, primary hypotheses, scientific opportunities The stress-disease cascade hypothesis
15:44271 views · 9mo ago · 15:44
Guest: Anna Monzel
2025 MiSBIE Symposium Part III – Immune cell bioenergetics Session Chair – Darshana Kapri Immune mitochondrial phenotypes – Jack Devine Immune cell bioenergetics (seahorse) in mitochondrial diseases – Anna Monzel Life adversity moderates the relationship between immune cell mitochondrial respiration and mood symptoms – Cynthia Liu
25:01432 views · 9mo ago · 25:01
Guest: Natalia Bobba Alves
2025 MiSBIE Symposium Part V – The energetics of acute stress reactivity Session Chair – Evan Shaulson The MiSBIE stress reactivity protocol & Physiological and neuroendocrine reactivity in health and mitochondrial disease – Natalia Bobba-Alves (zoom) Saliva and blood cell-free mtDNA reactivity to acute psychosocial stress – David Shire FGF21 reactivity to acute psychosocial stress – Mangesh Kurade 2:40 GDF15 reactivity to acute psychosocial stress – Caroline Trumpff 2:50…
15:32396 views · 9mo ago · 15:32
Guests: Jack Devine, Immune Mitochondrial Phenotypes
2025 MiSBIE Symposium Part III – Immune cell bioenergetics Session Chair – Darshana Kapri Immune mitochondrial phenotypes – Jack Devine Immune cell bioenergetics (seahorse) in mitochondrial diseases – Anna Monzel Life adversity moderates the relationship between immune cell mitochondrial respiration and mood symptoms – Cynthia Liu
13:40208 views · 9mo ago · 13:40
Guest: Cynthia Liu
2025 MiSBIE Symposium Part III – Immune cell bioenergetics Session Chair – Darshana Kapri Immune mitochondrial phenotypes – Jack Devine Immune cell bioenergetics (seahorse) in mitochondrial diseases – Anna Monzel Life adversity moderates the relationship between immune cell mitochondrial respiration and mood symptoms – Cynthia Liu
12:40105 views · 9mo ago · 12:40
Guest: Mangesh Kurade
2025 MiSBIE Symposium Part V – The energetics of acute stress reactivity Session Chair – Evan Shaulson The MiSBIE stress reactivity protocol & Physiological and neuroendocrine reactivity in health and mitochondrial disease – Natalia Bobba-Alves (zoom) Saliva and blood cell-free mtDNA reactivity to acute psychosocial stress – David Shire FGF21 reactivity to acute psychosocial stress – Mangesh Kurade 2:40 GDF15 reactivity to acute psychosocial stress – Caroline Trumpff 2:50…
16:01496 views · 9mo ago · 16:01
Guest: Evan Shaulson
2025 MiSBIE Symposium Part VI – Opportunities and future directions The energetic cost of mitochondrial disorders across day and night: MDEE – Evan Shaulson Summary: Opportunities, collaborations, data sharing – Martin Picard
19:54216 views · 9mo ago · 19:54
Guests: Michel Thiebaut de Schotten, MitoBrain MRI Map
Part II – Looking inside the brain’s mitochondria Session Chair - Anna Monzel MitoBrain MRI map – Michel Thiebaut de Schotten (zoom) Mitochondrial energy transformation capacity influences brain activation during sensory, affective, and cognitive tasks – Ke Bo / Tor Wager
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