Chris Kresser M.S., L.Ac. is the co-founder of the California Center for Functional Medicine, the founder of Kresser Institute, the host of the top-ranked he…
25:40238 views · 1w ago · 25:40
In this episode of Revolution Health Radio, Chris examines emerging research on the connection between ADHD and gut health. Reviewing a meta-analysis involving 23 studies and nearly two million people, he explores why individuals with ADHD experience higher rates of gastrointestinal symptoms and what the findings may reveal about the gut-brain connection.
50:25315 views · 2w ago · 50:25
Guest: Dr. Ray Dorsey
In this episode of Revolution Health Radio, Chris Kresser sits down with neurologist Dr. Ray Dorsey, author of The Parkinson’s Plan, to challenge the conventional view of Parkinson’s disease as primarily a consequence of aging and genetics. Dr. Dorsey makes the case that environmental exposures—including pesticides, industrial solvents, air pollution, and heavy metals—play a major role in the development and progression of Parkinson’s disease.
30:05424 views · 1mo ago · 30:05
In this episode of Revolution Health Radio, Chris breaks down two new studies of older adults that examine protein and micronutrient intake on plant-based diets. The findings raise important questions about protein quality, B12, calcium, zinc, vitamin D, and other nutrients—especially as aging increases protein needs and can reduce nutrient absorption.
📄 Mentioned papers: doi:10.3945/ajcn.115.119461 · doi:10.1016/j.jamda.2013.05.021 · doi:10.1016/j.cdnut.2026.109446 · doi:10.1016/j.jnha.2024.100361
25:30448 views · 1mo ago · 25:30
In this episode of Revolution Health Radio, Chris takes a nuanced look at melatonin and challenges the idea that because it is a naturally occurring hormone, it is automatically safe for routine, long-term use.
26:31405 views · 1mo ago · 26:31
In this episode of Revolution Health Radio, Chris takes a deep dive into the latest research on ultra-processed foods, their potential impact on health, what distinguishes ultra-processed foods from minimally-processed and traditionally-processed foods, and why a Nutrition Facts label may not capture everything that matters about a food.
23:54481 views · 2mo ago · 23:54
In this episode of Revolution Health Radio, Chris Kresser explores what biological age really means and examines the research behind today's most popular longevity claims. He explains how epigenetic clocks and DNA methylation are used to estimate biological aging, why these tests may be less precise for individuals than they appear, and what studies like the CALERIE trial tell us about slowing the aging process.
33:52423 views · 2mo ago · 33:52
In this episode of Revolution Health Radio, Chris breaks down the science behind joint pain, osteoarthritis, and cartilage degeneration while challenging one of the most common assumptions about joint health—that glucosamine and chondroitin are the gold standard for protecting cartilage and relieving pain.
56:14388 views · 3mo ago · 56:14
Guest: Dr. David Perlmutter
In this episode of Revolution Health Radio, Chris Kresser sits down with renowned neurologist and bestselling author Dr. David Perlmutter to discuss the emerging science of microglia—the brain's immune cells—and why they may hold the key to preventing cognitive decline and Alzheimer's disease. Drawing from his new book, Brain Defenders, Dr.
📄 Mentioned papers: Paper on jamanetwork.com · Paper on pmc.ncbi.nlm.nih.gov
25:08202 views · 4mo ago · 25:08
What if one of the most overlooked risk factors for cognitive decline isn’t in the brain—but in the mouth? In this episode of Revolution Health Radio, Chris Kresser explores the emerging science linking oral health to brain health. He examines how chronic gum disease may contribute to cognitive decline, Alzheimer’s disease, and Parkinson’s disease through systemic inflammation, direct bacterial migration to the brain, and disruption of the oral-gut-brain axis.
📄 Mentioned papers: Paper on science.org · Paper on onlinelibrary.wiley.com · Paper on tandfonline.com · Paper on link.springer.com
20:23336 views · 5mo ago · 20:23
In this episode of Revolution Health Radio, Chris takes a deep dive into the science of dietary fiber, fiber supplements, and microbiome health. He explains why the benefits seen in high-fiber diets may come from whole foods rather than isolated fiber supplements, and why aggressively increasing fiber intake can worsen bloating, gas, and gut dysfunction for some people.
📄 Mentioned papers: Paper on link.springer.com · 31809-9 fulltext · Paper on nature.com
26:11241 views · 6mo ago · 26:11
In this episode we discuss The role of the microbiome in immune regulation Intestinal permeability (“leaky gut”) and its systemic effects Lipopolysaccharides and chronic inflammation The link between gut dysfunction and chronic diseases “Inflammaging” and the gut’s role in aging How modern life disrupts gut health Practical strategies to support the gut-immune axis
📄 Mentioned papers: Paper on link.springer.com · Paper on mdpi.com · Paper on pubmed.ncbi.nlm.nih.gov · Paper on frontiersin.org
30:25184 views · 6mo ago · 30:25
In this episode of Revolution Health Radio, Chris unpacks the latest science on microplastics. He explores groundbreaking studies linking microplastic accumulation to increased risk of cardiovascular disease, inflammation, and potential neurological impacts, while clarifying what we know—and what we don’t.
📄 Mentioned papers: Paper on mdpi.com · Paper on nejm.org · Paper on nature.com · Paper on sciencedirect.com
16:40180 views · 6mo ago · 16:40
In this episode of Revolution Health Radio, Chris Kresser explores the growing phenomenon of orthosomnia, a condition driven by the obsessive pursuit of perfect sleep metrics. While devices like the Oura Ring, Whoop, and Apple Watch offer valuable insights, they can also increase anxiety and disrupt the very sleep they aim to improve. Chris breaks down the science behind sleep anxiety, including the role of cortisol and the hyperarousal model of insomnia.
📄 Mentioned papers: Paper on link.springer.com · Paper on sciencedirect.com · Paper on sciencedirect.com · Paper on mdpi.com
24:38224 views · 6mo ago · 24:38
In this episode of Revolution Health Radio, Chris explores the science behind GLP-1 medications, including their powerful effects on appetite, weight loss, and cardiometabolic risk. He also uncovers the critical blind spots in the current conversation, including new research on long-term side effects, nutrient deficiencies, muscle loss, and the high rate of weight regain after discontinuation.
20:53229 views · 7mo ago · 20:53
For decades, public health guidelines have warned that reducing sodium intake is essential for preventing high blood pressure and cardiovascular disease. But a closer look at the scientific evidence reveals a far more complex story. In this episode of Revolution Health Radio, Chris explores the history behind the low-sodium movement and examines the research that shaped modern dietary guidelines.
📄 Mentioned papers: 30467-6 abstract · Paper on jamanetwork.com · Paper on jamanetwork.com
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