National Library of Medicine

2026 NLM Ada Lovelace Computational Health Lecture | Lessons from Genomic Medicine for Clinical AI

353 views · 19h ago · 59:58

Guest: Casey Overby Taylor

The National Library of Medicine (NLM) is pleased to host the 2026 NLM Ada Lovelace Computational Health Lecture. This lecture series, presented by NLM’s Division of Intramural Research, recognizes the contributions of computer scientists in research on health and biomedicine. The series features women in STEM sectors and invites them to share their pioneering research with NIH and beyond.

Using NCBI Databases with Tools that Predict the Functional Impact of Genomic Variants

486 views · 2d ago · 9:57

Explore how NCBI databases, annotation tools, and computational predictors help researchers investigate genomic variants. Learn how these resources provide complementary evidence about potential effects on proteins, RNA splicing, and gene regulation—and how newer approaches relate to familiar tools.

Transforming Healthcare from the Outside | Lindberg-King Lecture in Medical Informatics

506 views · 3d ago · 1:08:30

The Observer: Transforming Healthcare from the Outside Lecture Overview: The U.S. healthcare system continues to face significant challenges, including rising costs, variable quality, and an under-realized return on substantial investment. At the same time, advances in artificial intelligence are rapidly reshaping industries and hold growing promise for healthcare.

Apply for Controlled Access Data in dbGaP

1.2K views · 2mo ago · 3:50

This video shows you step-by-step how to request access to controlled, human data in dbGaP, the Database of Genotypes and Phenotypes at NCBI. dbGaP home page

Apply for Controlled Access Data in dbGaP - Version 2

978 views · 2mo ago · 4:23

This is a minor update to the video, Apply for Controlled Access Data in dbGaP, and shows you step-by-step how to request access to controlled, human data in dbGaP, the Database of Genotypes and Phenotypes at NCBI. Previous video version, Apply for Controlled Access Data in dbGaP,

Renew Authorized Access in dbGaP

510 views · 2mo ago · 3:17

This video walks through the steps needed to complete a renewal of authorized access for a project in dbGaP, the Database of Genotypes and Phenotypes. dbGaP home page

The Human Genome Project: problems and prospects (1988)

2K views · 2mo ago · 1:44:13

Charles Cantor presents a highly technical lecture on the human genome project. The human genome has approximately three billion base pairs which are polymorphic with a small percentage in variable positions. The steps in the analysis are the development of maps: (1) physical, (2) restriction, (3) cosmid, and (4) linkage. The cosmid map is cloned DNA arranged in order. For example, in E. coli the researcher can establish fragments and determine order.

The Thomas Jefferson collection at the Library of Congress (Medical History Seminar, Feb. 4, 2008)

936 views · 2mo ago · 59:51

Forged in fire: the Thomas Jefferson collection at the Library of Congress The nucleus of the Library of Congress was forged in fire. In 1815 Congress purchased Thomas Jefferson's personal library--then the largest private book collection available in North America--to replace the congressional library destroyed when the British burned the U.S. Capitol the previous year. When Mr. Jefferson's books arrived in Washington, D.C., Library of Congress found its center and impetus.

Bridging the East-West divide: genesis of a Chinese hospital in San Francisco (Apr. 16, 2008)

627 views · 2mo ago · 1:27:46

Bridging the East-West divide: genesis of a Chinese hospital in San Francisco (Medical History Seminar, Apr. 16, 2008) History of Medicine Seminars - Archive - National Library of Medicine Hospitals, Community -- history Asian -- history Disease Outbreaks -- history Emigrants and Immigrants -- history History, 19th Century History, 20th Century Plague -- history San Francisco

The Strange Career of Dr. "Mom" Chung (Medical History Seminar, June 11, 2008)

813 views · 2mo ago · 1:01:44

From white woman's burden to orientalized motherhood: the strange career of Dr. "Mom" Chung (Medical History Seminar, June 11, 2008) During World War II, Mom Chung's was the place to be in San Francisco. Soldiers, movie stars, and politicians gathered at her home to socialize, to affirm their dedication to the Allied cause, and to express their affection for their adopted mother, Dr. Margaret Chung.

dbGaP Orientation: Getting Started

462 views · 3mo ago · 3:02

Learn how to register a study in dbGaP as a Principal Investigator. This video walks through the registration process, including working with a Genomic Program Administrator (GPA), completing required study information, preparing Institutional Certification documents, and submitting your registration for review and approval.

NLM's 2017 - 2027 Strategic Plan Accomplishments

868 views · 3mo ago · 3:06

Every day, NLM’s work moves fast. Decisions, deadlines — the next request, the next discovery. It’s rare that we stop to see the shape of what we’ve built together. So, for a moment, we will. A decade ago, under former NLM Director Dr. Patti Brennan, the National Library of Medicine set a ten-year course to advance biomedical discovery through data, expand its reach, and build the workforce and infrastructure for a data-driven future. This is what that decade became.

2026 NLM Colloquia Series | Recipes for Building Agents for Biomedical Discovery

953 views · 3mo ago · 1:11:06

Abstract This talk will discuss building AI agents for biomedical discovery, focusing on integrating language models with biological knowledge and domain-specific tools to support research workflows. Also, I will share what worked, what failed, what we learned about reliability, evaluation, and human-agent collaboration, and where the field may be heading in the near future.

2026 NLM/MLA Joseph Leiter Lecture | How AI Is Reshaping Biomedical Discovery

1.1K views · 4mo ago · 56:16

2026 NLM/MLA Joseph Leiter Lecture | How AI Is Reshaping Biomedical Discovery Today, major breakthroughs in understanding disease biology and developing treatments require significant wet lab exploration. Emerging AI algorithms for Electronic Health Records (EHR), image processing, and molecular modeling can potentially provide an alternative means for exploring a large space of possible solutions, enabling scientists to prioritize the most promising hypotheses for testing.

Politics of Yellow Fever in Alexander Hamilton’s America

924 views · 4mo ago · 3:46

In 1793, yellow fever ravaged Philadelphia. During this time, citizens confronted the epidemic in the absence of an effective cure or consensus about the origins of the disease, while medical professionals, early political parties, and private citizens seized on the epidemic to advance their respective agendas. As a result, Philadelphia’s sick and dying received medical care informed as much by politics as by the best available science.